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ANC Workshop Talk: Mark van Rossum and Colin Mclean, Chair: Seymour Knowles Barley

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What
  • ANC Workshop Talk
When Jun 26, 2012
from 11:00 AM to 12:00 PM
Where IF 4.31/4.33
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Mark van Rossum

Representational capacity of neural codes in the cortex

The coding of sensory stimuli in the neural response is a fundamental property of neural systems that impacts many of its properties. The coding scheme also determines how many different stimuli a population of neurons can represent. Although the coding of single stimuli has been studied extensively, coding of multiple stimuli has been studied far less. Here we study the representational capacity in the visual system when stimulus pairs are represented simultaneously. We assume that the response to the individual stimuli is given, and that the neurons interacts non-linearly to form the response to the pair. Using a Bayesian read-out we find that using a linear sum leads to a smaller capacity, than a maximum-like interaction. Thus non-linear interaction improve coding capacity. The results provide a novel interpretation for the non-linear interaction observed experimentally.

 

Colin Mclean

Preliminary analysis of static PPI pre synaptic data sets for the SynSys project

Large static protein-protein interaction (PPI) data sets generated by the EU consortium's of EuroSPIN and SynSys, are available and are starting to be analysed. These data sets consists of about 2000 proteins from the mammalian pre synaptic densities; currently one of the largest experimentally generated pre synaptic gene lists. The Edinburgh group within these consortia, have a responsible for cleaning, processing and analysis of these data sets. This talk aims to show preliminary work on handing such data for the SynSys consortium and application of our community detection suite to model these networks.