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ANC Workshop: James Raymond and David Sterratt, Chair: Alba Crespi

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What
  • ANC Workshop Talk
When Jan 17, 2017
from 11:00 AM to 12:00 PM
Where IF 4.31/4.33
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James Raymond:

Using computational models to study individual differences: the case of trait anxiety

Computational methods are increasingly being applied to the study of psychiatric disorders. Often, this involves fitting models to the behavior of individuals with subclinical self-reported character traits which are known vulnerability factors for the development of psychiatric conditions. The relationship between such self-report measures and the behavioral processes captured in computational models has not been well-characterized and should not be taken for granted. 

This talk will consider which aspects of long-term behavior are captured by scores on the self-report questionnaire measure of ‘trait anxiety’ and how these may emerge from underlying computational processes susceptible to cross-sectional analysis.

 

David Sterratt:

“How can rule-based models help computational neuroscience?”

The molecular signalling pathways of synapses contain molecules that exhibit that exhibit combinatorially large numbers of states. I will give a brief introduction into "rule-based" languages such as Kappa (Danos et al) and BNGL (Faeder et al), explaining how they can be used to describe concisely and simulate pathways, obviating the problem of combinatorially large numbers of states. I will give a brief description of how I have linked a rule-based system into a conventional neural simulator (NEURON).