Modelling ocular dominance plasticity (PhD)

Ocular dominance is very important for our brain development and world perception. It helps our brain to most efficiently use the information it receives from eyes about the world around us. When one of the eyes does not see properly, its signal is less important for our brain. In this situation our brain switches to the better eye to see the world more accurately and to be able to respond faster and in more adequate way to the situation. But this phenomenon of switching takes place only during so called critical period for ocular dominance, when plasticity of visual cortex strongly increases. This problem is known for a long time now, but the explanations suggested so far are highly unsatisfactory.
The aim of this project is to develop a computational theory to explain circumstances that affect the start and end of the critical period plasticity, based on simulations of neuronal networks with synaptic plasticity and  homeostasis and will use the recent increase in experimental data on this issue. The project will also investigate the role of inhibitory plasticity in critical period occurrence.

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