The Centre for Interactive Image Analysis has recieved start-up funding from the SHEFC Research Development Grant program to establish functional MRI at the Western General Hospital, and to establish and research advanced analysis and visualisation capabilities for functional MRI data. The Centre is a cooperative venture between the Institute for Adaptive and Neural Computation and the Brain Imaging Research Centre. The project involves the following participants:
Dr Nigel Goddard
(Adaptive and Neural
Dr Ian Marshall (Medical Physics)
Dr Enrico Simonotto (Adaptive and Neural Computation)
Dr Heba Lakany(Medical Physics
Professor Ian Deary (Psychology)
Professor Ian Whittle (Clinical Neurosciences)
Professor Klaus Ebmeier (Psychiatry)
Dr John Starr (Geriatrics)
Dr Richard Shillcock (Cognitive Science)
Professor David Willshaw (Adaptive and Neural Computation)
Dr Chris Williams (Adaptive and Neural Computation)
Professor Richard Kenway (Edinburgh Parallel Computing Centre)
Dr Joanna Wardlaw (Clinical Neurosciences)
Recently a new experimental and diagnostic fMRI modality, realtime analysis and visualisation, has been demonstrated. This new capability is expected to open up many new areas of activity, including surgical planning, diagnosis, training, and more sensitive scientific studies. Provision of advanced, realtime analysis and visualisation capabilities of imaged data to laboratory and office desktops will be an enabling infrastructure that will foster many new avenues of research.
fMRI studies where the results can be obtained within a few seconds after scanning makes it possible to use the results of one experiment to guide the conduct of subsequent ones within the same scanning session. For example, a potentially large battery of tests can be worked through, where tests can be discarded on the basis of previous results; patterns of brain activity which change substantially over a short time scale can be tracked; task parameters can be calibrated to an individual's pattern of brain activity, which may be particularly useful in studies involving patients where complications arise not only due to illness, but also due to increased anxiety levels and medications. To investigate cognitive functions, many of which are subserved by multiple brain regions, the changing interactions between different parts of the brain can be monitored. Realtime or near realtime image analysis and visualisation enables these new, dynamic experimental and clinical studies.
The project is directed by Dr Nigel Goddard, Division of Informatics, and Dr Ian Marshall, Department of Medical Physics. Dr Goddard is a newly appointed member of staff with special expertise in the application of parallel computing to functional imaging research. His previous appointment was at the Pittsburgh Supercomputing Center, USA, where he demonstrated the feasibility of the realtime approach to be extended here. Dr Marshall is a medical physicist with special expertise in MRI data capture and the analysis of medical images. He works in close collaboration with clinicians at the Western General Hospital, where the new scanner is based. He has been responsible for imaging sequence development on the older NHS scanner.
Nigel Goddard, Greg Hood, Jonathan Cohen, William Eddy, Christopher Genovese, Douglas Noll, Leigh Nystrom Online Analysis of Functional MRI Datasets on Parallel Platforms Journal of Supercomputing, 11(3): 295-318, November 1997
© 2000 Institute for Adaptive and Neural Computation